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A6428 Sigma

Aflatoxin M1

from Aspergillus flavus

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Properties

Related Categories A-AM, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cancer Research, Carcinogens,
biological source   from Aspergillus flavus
InChI Key   MJBWDEQAUQTVKK-IAGOWNOFSA-N
storage temp.   2-8°C

Description

Biochem/physiol Actions

Hepatocarcinogen.

Preparation Note

Aspergillus flavus metabolite.

Warning

Possibly carcinogenic.

Application

Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

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Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGI
WGK Germany 
3
Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

HPLC Analysis of Aflatoxins on Ascentis® Express C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Aflatoxins on Ascentis® Express C18
Keywords: Chromatography, High performance liquid chromatography, Separation

LC/MS Analysis of Aflatoxin M1 in Milk on Ascentis® Express HILIC after SPE using Supel™ Tox AflaZea, Quantifying Picogram Concentrations

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Aflatoxin M1 in Milk on Ascentis® Express HILIC after SPE using Supel™ Tox AflaZea, Quantifying Picogram Concentrations
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites, Precipitation, Sample preparations, Separation, Solid phase extractions

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Peer-Reviewed Papers
15

References

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