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A6779 Sigma-Aldrich

Adenosine 5′-triphosphate, periodate oxidized sodium salt

≥97%

Synonym: Adenosine 5′-triphosphate-2′,3′-dialdehyde, oATP

  • CAS Number 71997-40-5

  • Empirical Formula (Hill Notation) C10H14N5O13P3

  • Molecular Weight 505.17

  •  MDL number MFCD00056956

  •  eCl@ss 32160414

  •  PubChem Substance ID 24891137

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleotides, Oligonucleotides, Nucleotides More...
assay   ≥97%
storage temp.   −20°C
SMILES string   [Na].Nc1ncnc2n(cnc12)[C@H](O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C=O)C=O
InChI   1S/C10H14N5O13P3.Na.H/c11-9-8-10(13-4-12-9)15(5-14-8)7(2-17)26-6(1-16)3-25-30(21,22)28-31(23,24)27-29(18,19)20;;/h1-2,4-7H,3H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;/t6-,7+;;/m0../s1
InChI key   IHQATUPGVKMGLT-AUCRBCQYSA-N

Description

General description

Adenosine 5′-triphosphate 2′,3′ dialdehyde is a derivative of dialdehyde.

Application

Adenosine 5′-triphosphate, periodate oxidized sodium salt has been used:
• as an antagonist of the purinergic receptor, P2 × 7 to inhibit P2 × 7 pathway
• as a nonspecific agonist to assess the activity of P2×7-R by the mobilization of Ca2+
• to evaluate the physiological significance of elevated intracellular ATP levels
• increased P2rx7 expression for osteoclastogenesis in Flcn-deficient cells

Packaging

25, 100 mg in poly bottle

Biochem/physiol Actions

Adenosine 5′-triphosphate 2′,3′ dialdehyde is considered as an inhibitor of P2 × 7 receptor.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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