• USA Home
  • A7475 - Anthopleurin-A trifluoroacetate salt

EMAIL THIS PAGE TO A FRIEND
A7475 Sigma-Aldrich

Anthopleurin-A trifluoroacetate salt

>88% (HPLC)

Synonym: AP-A trifluoroacetate salt, Anthopleura toxin A trifluoroacetate salt

  • Empirical Formula (Hill Notation) C220H326N64O67S6 · xC2HF3O2

  • Molecular Weight 5131.72 (free base basis)

  •  MDL number MFCD00240628

  •  NACRES NA.77

Purchase

Description

Amino Acid Sequence

Gly-Val-Ser-Cys-Leu-Cys-Asp-Ser-Asp-Gly-Pro-Ser-Val-Arg-Gly-Asn-Thr-Leu-Ser-Gly-Thr-Leu-Trp-Leu-Tyr-Pro-Ser-Gly-Cys-Pro-Ser-Gly-Trp-His-Asn-Cys-Lys-Ala-His-Gly-Pro-Thr-Ile-Gly-Trp-Cys-Cys-Lys-Gln [Disulfide bridges: 4-46, 6-36, 29-47]

General description

Synthetic peptide toxin that was originally isolated from the sea anemone, Anthopleura xantho­grammica.

Application

Anthopleurin-A is a toxin used to study the gating mechanisms of sodium channels. Anthopleurin-A slows the repolarization phase of nerve and muscle action potentials by inactivating the sodium channel.

Biochem/physiol Actions

Shown to have inotropic effects and not chronotropic effects on mammalian heart preparations.

Other Notes

supplied as trifluoroacetate salt

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?