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A7631 Sigma-Aldrich

(+)-Sodium L-ascorbate

crystalline, ≥98%

Synonym: L(+)-Ascorbic acid sodium salt, Vitamin C sodium salt

  • CAS Number 134-03-2

  • Empirical Formula (Hill Notation) C6H7NaO6

  • Molecular Weight 198.11

  •  Beilstein/REAXYS Number 3767246

  •  EC Number 205-126-1

  •  MDL number MFCD00082340

  •  eCl@ss 34058010

  •  PubChem Substance ID 24891261

  •  NACRES NA.79

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Properties

Related Categories Ascorbate, Biochemicals and Reagents, Cell Biology, Chemical Biology, Chemical Synthesis,
Quality Level   300
biological source   synthetic
assay   ≥98%
form   crystalline
application(s)   HPLC: suitable
color   white to off-white
mp   220 °C (dec.) (lit.)
SMILES string   [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-]
InChI   1S/C6H8O6.Na/c7-1-2(8)5-3(9)4(10)6(11)12-5;/h2,5,7-10H,1H2;/q;+1/p-1/t2-,5+;/m0./s1
InChI key   PPASLZSBLFJQEF-RXSVEWSESA-M

Description

General description

Ascorbic acid, also known as vitamin C, is a water-soluble vitamin. L-Ascorbic acid is a reducing agent.

Application

(+)-Sodium L-ascorbate has been used:
• as a component of cutting solution for storing brain slices of rats
• as a component of patch pipette internal solution for imaging Ca2+ transients evoked by action potential in rat brain slices
• as a supplement for arterial smooth muscle cell (SMC) cultures to encourage collagen production

Packaging

1 kg in poly bottle

25, 100, 500 g in poly bottle

Biochem/physiol Actions

Ascorbic acid exhibits anti-oxidant properties. It is a primary substrate for detoxifying hydrogen peroxide. Ascorbic acid is a co-factor for the synthesis of adrenal steroids and catecholamines. L-Ascorbic acid (Vitamin C) is a water soluble molecule used in a wide variety of applications, including cell culture, as a reducing agent that helps reduce oxidative stress. L-Ascorbate can be regenerated by biological systems.

Caution

May darken in storage.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 1
RTECS 
CI7671000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

A Biologically-Inspired Electrochemical Half-Cell for Light-Driven Generation of Hydrogen

An economy based on hydrogen has long been touted as one of the most promising routes to a sustainable energy future. Hydrogen gas (H2) is a particularly clean source of energy that can be utilized e...
Rebecca A. Grimme1 and John H. Golbeck*1,2
Material Matters 2008, 3.4, 78.
Keywords: Absorption, Biochemistry, Catalysis, Deposition, Diffusion, Ligands, Mass spectrometry, Metabolism, Methods, Molecular biology, Nucleic acid denaturation, Photosynthesis, Recombination, Reductions, Semiconductor, Support, Type

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

Protocols

Core functionalization of Polyester-16-hydroxyl-1-acetylene bis-MPA dendron

Theoretical MW: 1797.79 g/mol Average Molecular Formula: C78H124O46 Number of hydroxyl groups: 16 Number of acetylene groups: 1
Keywords: Catalysis, Chromatography, Click chemistry, Cycloadditions, Flash chromatography, Nuclear magnetic resonance spectroscopy, Solvents

Core functionalization of Polyester-32-hydroxyl-1-acetylene bis-MPA dendron

This monodisperse compound has multiple surface hydroxyl groups and a single alkyne focal point function. The alkyne function is well suited for “Click chemistry” catalytic cycloaddition to azides (s...
Keywords: Catalysis, Chromatography, Click chemistry, Cycloadditions, Flash chromatography, Nuclear magnetic resonance spectroscopy, Solvents

Peer-Reviewed Papers
15

References

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