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A7902 Sigma-Aldrich

2-Amino-2-norbornanecarboxylic acid

amino acid transport inhibitor

Synonym: 2-Aminobicyclo[2.2.1]heptane-2-carboxylic acid, BCH

  • CAS Number 20448-79-7

  • Empirical Formula (Hill Notation) C8H13NO2

  • Molecular Weight 155.19

  •  MDL number MFCD00167580

  •  PubChem Substance ID 24891291

  •  NACRES NA.26

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Properties

Related Categories A - H, Amino Acids, Biochemicals and Reagents, Modified Amino Acids
Quality Level   100
assay   ≥98% (TLC)
form   powder
application(s)   ligand binding assay: suitable
color   white to brown
mp   >300 °C (lit.)
SMILES string   NC1(C[C@@H]2CC[C@H]1C2)C(O)=O
InChI   1S/C8H13NO2/c9-8(7(10)11)4-5-1-2-6(8)3-5/h5-6H,1-4,9H2,(H,10,11)/t5-,6+,8?/m1/s1
InChI key   MPUVBVXDFRDIPT-RSHNMJPRSA-N

Description

General description

2-Amino-2-norbornanecarboxylic acid is a potential large amino acid transporters inhibitor. It may suppress tumor progression and apoptosis.

Packaging

1 g in glass bottle

100, 250 mg in glass insert

Biochem/physiol Actions

2-Amino-2-norbornanecarboxylic acid (BCH) is a Na(+)-independent system L specific substrate used with other system specific substrates such as the system A specific substrate α-(methylamino) isobutyric acid and system N specific substrate L-glutamic acid gamma-monohydroxamate to help identify, differentiate and characterize amino acid transport systems in cells.

Quality

Mixture of exo- and endo-isomers.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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