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A8003 Sigma-Aldrich

Allopurinol

xanthine oxidase inhibitor

Synonym: 1H-Pyrazolo(3,4-d)pyrimidin-4-ol, 4-Hydroxypyrazolo(3,4-d)pyrimidine, 4-Hydroxypyrazolo[3,4-d]pyrimidine, HPP

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Properties

Related Categories Biochemicals and Reagents, Enzyme Inhibitors, Enzyme Inhibitors by Type, Enzymes, Inhibitors, and Substrates, Substrate Analogs More...
Quality Level   200
biological source   synthetic (organic)
assay   ≥99% (TLC)
form   powder
mp   >300 °C (lit.)
solubility   1 M NaOH: soluble 50 mg/mL, clear to very slightly hazy, colorless to faintly yellow
storage temp.   room temp
SMILES string   O=C1NC=Nc2[nH]ncc12
InChI   1S/C5H4N4O/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
InChI key   OFCNXPDARWKPPY-UHFFFAOYSA-N
Gene Information   human ... XDH(7498)

Description

Packaging

5, 25 g in glass bottle

Biochem/physiol Actions

Inhibitor of xanthine oxidase and de novo pyrimidine biosynthesis. A classical agent in treatment of hyperuricemia and gout.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 2
RTECS 
UR0785000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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