EMAIL THIS PAGE TO A FRIEND
A8185 Sigma-Aldrich

Ala-Gln

BioReagent, suitable for cell culture, suitable for insect cell culture

Synonym: Alanyl-glutamine, Glutamine-S

  • CAS Number 39537-23-0

  • Empirical Formula (Hill Notation) C8H15N3O4

  • Molecular Weight 217.22

  •  MDL number MFCD00133046

  •  PubChem Substance ID 24891211

  •  NACRES NA.75

Purchase

Properties

Related Categories Amino Acids, Amino Acids and Vitamins, Cell Culture, Companion Products and Reagents, Insect Platform,
Quality Level   200
product line   BioReagent
assay   ≥98% (HPLC)
form   powder
application(s)   cell culture | insect: suitable
  cell culture | mammalian: suitable
color   white to off-white
storage temp.   room temp
SMILES string   NC(CC[C@H](NC([C@@H](N)C)=O)C(O)=O)=O
InChI   1S/C8H15N3O4/c1-4(9)7(13)11-5(8(14)15)2-3-6(10)12/h4-5H,2-3,9H2,1H3,(H2,10,12)(H,11,13)(H,14,15)/t4-,5-/m0/s1
InChI key   HJCMDXDYPOUFDY-WHFBIAKZSA-N

Description

Application

Ala-Gln has been used:
• as a supplement in NeuralQ medium
• as a component in growth medium and incubation medium (IM) for retinal cell lines
• for experimental treatment of retinal cell lines respectively

Packaging

1 kg in poly drum

5, 100 g in poly bottle

Biochem/physiol Actions

Alanyl-glutamine (Ala-Gln) is a dipeptide that is used as a substitute for glutamine in mammalian cell culture media, because of the instability of glutamine in solution and the formation of ammonia as a breakdown product of glutamine in solution, which can have deleterious effects on cells in culture. Ala-Glu is stable to heat sterilization and is less ammonia genic than glutamine, which contributes to its advantages as a media component. Ala-Gln has been utilized to investigate polymorphonuclear leucocyte and myeloperoxidase activity in vitro.

Analysis Note

This product is cell culture tested (0.5 mg/ml) and insect cell culture tested (0.2 mg/ml). It is appropriate for use in cell culture and insect cell culture applications at 2-10 mM.

Legal Information

NeuralQ is a trademark of GlobalStem

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number

Request a Serum Sample

Pipette Controller from Brand
Protocols & Articles

Articles

PLTMax® Human Platelet Lysate (hPL): A Superior Serum-Free Media Supplement for Robust Mesenchymal Stem Cell Expansion

Introduction Methods       Human MSC Expansion in Human Platelet Lysate       Human MSC Differentiation       FACS Mesenchymal Stem Cell Marker Analysis Results Conclusions Materials
Aletta Schnitzler, Manjula Aysola, Anjali Verma, Tristan Lawson, Susan Rigby, Megan Pease, Sandhya Punreddy, Julie Murrell, Martha Rook
Stem Cell Bioprocessing Group
Keywords: Cell culture, Cell disruption, Clinical, Culture media, Flow cytometry, Gene expression, Growth factors, Polymerase chain reaction, Stem cell biology

Protocols

Induced Pluripotent Stem Cell Reprogramming Protocols

Introduction Methods     Reprogramming of Human Fibroblasts using Non-Integrating Self-Replicating RNA Vectors     Reprogramming of Peripheral Blood Mononuclear Cells (PBMCs) using STEMCCA Lentiviral...
Keywords: Apoptosis, Cell culture, Culture media, Gene expression, Growth factors, Immunocytochemistry, Polymerase chain reaction, Respiratory, Transduction, Transfection

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?