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A8846 Sigma-Aldrich

ProteoMass Angiotensin II MALDI-MS Standard

vial of 10 nmol

Synonym: Angiotensin II, mass spec standard

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Properties

Related Categories Mass Spectrometry, Molecular Biology, Peptide and Protein Standards for Mass Spectrometry Analysis, Proteomics
Quality Level   100
mol wt   monoisotopic mol wt 1,045.5423 Da
packaging   vial of 10 nmol
SMILES string   CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](N)CC(O)=O)C(C)C)C(=O)N[C@@H](Cc2c[nH]cn2)C(=O)N3CCC[C@H]3C(=O)N[C@@H](Cc4ccccc4)C(O)=O
InChI   1S/C50H71N13O12/c1-5-28(4)41(47(72)59-36(23-31-25-54-26-56-31)48(73)63-20-10-14-38(63)45(70)60-37(49(74)75)22-29-11-7-6-8-12-29)62-44(69)35(21-30-15-17-32(64)18-16-30)58-46(71)40(27(2)3)61-43(68)34(13-9-19-55-50(52)53)57-42(67)33(51)24-39(65)66/h6-8,11-12,15-18,25-28,33-38,40-41,64H,5,9-10,13-14,19-24,51H2,1-4H3,(H,54,56)(H,57,67)(H,58,71)(H,59,72)(H,60,70)(H,61,68)(H,62,69)(H,65,66)(H,74,75)(H4,52,53,55)/t28-,33-,34-,35-,36-,37-,38-,40-,41-/m0/s1
InChI key   CZGUSIXMZVURDU-JZXHSEFVSA-N
Gene Information   human ... AGTR1(185)

Description

General description

Angiotensin II (Ang II) is part of the renin-angiotensin cascade. It is an octapeptide. Ang II is present in high concentration in cardiac tissue.

Application

ProteoMass Angiotensin II MALDI-MS Standard has been used:
• as peptide calibration standard for MALDI-MS instruments
• as a reference standard in Liquid chromatography–mass spectrometry (LC-MS/MS) analysis for characterizing RNase and NC1 domain of collagen IV
• as a standard in testing infrared (IR) laser desorption/ionization (IR-LDI) method

Biochem/physiol Actions

Angiotensin II (Ang II) maintains cardiac functionality by coordinating with the angiotensin II receptors. Ang II is recommended for patients with vasodilatory shock.

Legal Information

ProteoMass is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Ultra-pure MALDI Matrices

One of the most important aspects of our ultra-pure MALDI matrix substances is their ability to dissolve rapidly and completely; a brief vortex mixing is typically sufficient. Actual performance of t...
Monika Baeumle, Alex Rueck
Analytix Volume 7 Article 5
Keywords: Crystallization, Digestions, High performance liquid chromatography, Mass spectrometry, Phase transitions, Proteomics, Sample preparations

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Peer-Reviewed Papers
15

References

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