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A9111 Sigma-Aldrich

(±)-AMPA hydrobromide

≥98% (HPLC)

Synonym: (±)-α-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid hydrobromide

  • CAS Number 171259-81-7

  • Empirical Formula (Hill Notation) C7H10N2O4 · HBr

  • Molecular Weight 267.08

  •  MDL number MFCD00055183

  •  PubChem Substance ID 329771033

  •  NACRES NA.77

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Properties

Related Categories A-AM, AMPA/Kainate Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   off-white to light tan
solubility   H2O: ≥10 mg/L
storage temp.   2-8°C
SMILES string   Br.Cc1onc(O)c1CC(N)C(O)=O
InChI   1S/C7H10N2O4.BrH/c1-3-4(6(10)9-13-3)2-5(8)7(11)12;/h5H,2,8H2,1H3,(H,9,10)(H,11,12);1H
InChI key   KUAHVIUZGLGASU-UHFFFAOYSA-N

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

(±)-AMPA is a potent excitatory amino acid that interacts selectively with central AMPA/kainate receptors.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the Glutamate Receptors (Ion Channel Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

Glutamate Receptors (Ion Channel Family)

The ion channel family of glutamate receptors ("€œionotropic"€ glutamate receptors or iGluR) comprises three major subtypes based on pharmacology and protein structure.
Keywords: Alzheimer Disease, Anticonvulsants, Atomic absorption spectroscopy, Clinical, Gene expression, Ligands, Neurotransmission, Physiological Processes, Schizophrenia

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