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A9187 Sigma-Aldrich

Adenosine 5′-triphosphate magnesium salt

≥95%, bacterial

Synonym: ATP magnesium salt

  • CAS Number 74804-12-9

  • Empirical Formula (Hill Notation) C10H16N5O13P3 · xMg2+

  • Molecular Weight 507.18 (free acid basis)

  •  MDL number MFCD00084767

  •  eCl@ss 32160414

  •  PubChem Substance ID 24891422

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Cofactors, Core Bioreagents, Enzymes, Inhibitors, and Substrates, Nucleosides and Nucleotides,
Quality Level   200
biological source   bacterial
assay   ≥95%
solubility   H2O: 50 mg/mL
storage temp.   −20°C
SMILES string   [Mg].Nc1ncnc2n(cnc12)C3OC(COP(O)(=O)OP(O)(=O)OP(O)(O)=O)C(O)C3O
InChI   1S/C10H16N5O13P3.Mg.2H/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(26-10)1-25-30(21,22)28-31(23,24)27-29(18,19)20;;;/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H,23,24)(H2,11,12,13)(H2,18,19,20);;;
InChI key   CPGAIACWYFBIFN-UHFFFAOYSA-N

Description

Application

Adenosine 5′-triphosphate magnesium salt has been used:
• as a supplement in intracellular medium for Ca2+ retention assay and fluorescence wide field imaging analysis
• as a component in potassium methane sulfonate-based internal solution for in vitro electrophysiology of cortical neurons
• as a component in action potential intracellular solution

Packaging

1 g in poly bottle

100, 500 mg in poly bottle

Biochem/physiol Actions

Adenosine 5γ-triphosphate (ATP) is a central component of energy storage and metabolism in vivo. ATP is use in many cellular processes, respiration, biosynthetic reactions, motility, and cell division. ATP is a substrate of many kinases involved in cell signaling and of adenylate cyclase(s) that produce the second messenger cAMP. ATP provides the metabolic energy to drive metabolic pumps. ATP serves as a coenzyme in a wide array of enzymatic reactions.

P2 purinergic agonist; increases activity of Ca2+-activated K+ channels; substrate for ATP-dependent enzyme systems

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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