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A9950 Sigma-Aldrich

Aniracetam

≥98%

Synonym: 1-(4-Methoxybenzoyl)-2-pyrrolidinone, Ro 13-5057

  • CAS Number 72432-10-1

  • Empirical Formula (Hill Notation) C12H13NO3

  • Molecular Weight 219.24

  •  MDL number MFCD00153767

  •  PubChem Substance ID 24277955

  •  NACRES NA.77

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Properties

Related Categories AN-AZ, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
assay   ≥98%
originator   Roche
SMILES string   COc1ccc(cc1)C(=O)N2CCCC2=O
InChI   1S/C12H13NO3/c1-16-10-6-4-9(5-7-10)12(15)13-8-2-3-11(13)14/h4-7H,2-3,8H2,1H3
InChI key   ZXNRTKGTQJPIJK-UHFFFAOYSA-N
Gene Information   human ... GRM1(2911), GRM2(2912), GRM3(2913), GRM4(2914), GRM5(2915), GRM6(2916), GRM7(2917), GRM8(2918)
rat ... Gria1(50592)

Description

Application

Aniracetam has been used in the inhibition screening assays for kinase enzyme.

Packaging

50, 250 mg in poly bottle

Biochem/physiol Actions

Aniracetam is a piracetam analog and has low bioavailability due to rapid excretion. It enhances the cognitive thinking and is effective for treatment of sleep and behavioral disorders. Aniracetam is prescribed for anxiety and also enhances learning and memory in situations with induced damage of the brain.

Cognition enhancer (nootropic) that potentiates AMPA receptor mediated ion conductance and potentiates metabotropic glutamate receptor activity.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Roche. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 2
RTECS 
UY5781900
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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