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AV44026 Sigma-Aldrich

Anti-SLC22A3 antibody produced in rabbit

affinity isolated antibody

Synonym: Anti-3-Oct, Anti-EMT, Anti-EMTH, Anti-Solute carrier family 22 (extraneuronal monoamine transporter), member 3

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies to Drug Transport Proteins, Biochemicals and Reagents, Drug Transport Proteins & Reagents,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry: suitable
  western blot: suitable
species reactivity   human
mol wt   61 kDa
form   lyophilized powder
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
concentration   0.5 mg - 1 mg/mL
NCBI accession no.   NP_068812
UniProt accession no.   O75751
Gene Information   human ... SLC22A3(6581)

Description

General description

Solute carrier family 22 (extraneuronal monoamine transporter), member 3 (SLC22A3, Oct3, EMTH) is a transporter of organic cations (OCT) that in addition to endogenous cations include various origin cationic toxins and drugs. SLC22A3 is widely distributed in brain tissues. Examples of important molecules transported by OCT3 include endogenous amines, histamine, dopamine, serotonin, norepinephrine, and MPP+.

Specificity

Anti-SLC22A3 polyclonal antibody reacts with human solute carrier family 22, member 3 protein.

Immunogen

Synthetic peptide directed towards the N terminal of human SLC22A3.

Application

Anti-SLC22A3 polyclonal antibody is used to tag solute carrier family 22 (extraneuronal monoamine transporter), member 3 protein for detection and quantitation by Western blotting and in plasma by immunohistochemical (IHC) techniques. It is used as a probe to determine the roles of solute carrier family 22 (extraneuronal monoamine transporter), member 3 in transport of small organic cations such as endogenous amines.

Physical form

Lyophilized from PBS buffer with 2% sucrose

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sequence

Synthetic peptide located within the following region: PDHYWCRGPSAAALAERCGWSPEEEWNRTAPASRGPEPPERRGRCQRYLL

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Protocols

Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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