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B1542 Sigma-Aldrich

[Lys-des-Arg9]-Bradykinin

≥95% (HPLC)

Synonym: des-Arg10-Kallidin

  • CAS Number 71800-36-7

  • Empirical Formula (Hill Notation) C50H73N13O11

  • Molecular Weight 1032.20

  •  MDL number MFCD00079826

  •  PubChem Substance ID 329773191

  •  NACRES NA.32

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Properties

Related Categories Biochemicals and Reagents, Bradykinins, Bradykinnins - Receptor Antagonists, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
assay   ≥95% (HPLC)
storage temp.   −20°C
SMILES string   NCCCC[C@H](N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc3ccccc3)C(=O)N[C@@H](CO)C(=O)N4CCC[C@H]4C(=O)N[C@@H](Cc5ccccc5)C(O)=O
InChI   1S/C50H73N13O11/c51-22-8-7-17-33(52)42(66)58-34(18-9-23-55-50(53)54)46(70)63-26-12-21-40(63)48(72)62-25-10-19-38(62)44(68)56-29-41(65)57-35(27-31-13-3-1-4-14-31)43(67)60-37(30-64)47(71)61-24-11-20-39(61)45(69)59-36(49(73)74)28-32-15-5-2-6-16-32/h1-6,13-16,33-40,64H,7-12,17-30,51-52H2,(H,56,68)(H,57,65)(H,58,66)(H,59,69)(H,60,67)(H,73,74)(H4,53,54,55)/t33-,34-,35-,36-,37-,38-,39-,40-/m0/s1
InChI key   AILVBOHFGXNHCC-TZPCGENMSA-N
Gene Information   human ... KNG1 (includes EG:3827)(3827)

Description

Amino Acid Sequence

Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe

Packaging

1 mg in glass bottle

Biochem/physiol Actions

Bradykinin B1 receptor agonist.

[Des-Arg10]-kallidin is a bradykinin B1 receptor agonist. It strongly upregulates the B1 receptor and is blocked by a specific protein kinase C inhibitor. The upregulation is correlated with the induction of transcription factor nuclear factor κB (NF-κB).

Other Notes

Lyophilized from 0.1% TFA in H2O

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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