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B1814 Sigma-Aldrich

Bone Morphogenetic Protein 2 human

Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested

Synonym: BMP-2



Related Categories Cell Culture, Growth Factors and Cytokines, Reagents and Supplements, Recombinant Bone Morphogenetic Proteins (BMP), Transforming Growth Factors More...
biological source   human
recombinant   expressed in E. coli
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
mol wt   mol wt 26  kDa
packaging   pkg of 10 μg
storage condition   avoid repeated freeze/thaw cycles
impurities   Endotoxin, tested
color   white
solubility   water: soluble 0.100 mL, clear, colorless
suitability   cell culture tested
UniProt accession no.   P12643
storage temp.   −20°C
Gene Information   human ... BMP2(650)


Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.

Physical form

Lyophilized from a 0.2 μm filtered buffered solution.

Biochem/physiol Actions

Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
104 °F
Flash Point(C) 
40 °C

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