• USA Home
  • B1814 - Bone Morphogenetic Protein 2 human

EMAIL THIS PAGE TO A FRIEND
B1814 Sigma-Aldrich

Bone Morphogenetic Protein 2 human

Carrier Free, ≥98% (SDS-PAGE), recombinant, expressed in E. coli, lyophilized powder, cell culture tested

Synonym: BMP-2

Purchase

Properties

Related Categories Cell Culture, Growth Factors and Cytokines, Reagents and Supplements, Recombinant Bone Morphogenetic Proteins (BMP), Transforming Growth Factors More...
biological source   human
recombinant   expressed in E. coli
assay   ≥98% (SDS-PAGE)
form   lyophilized powder
mol wt   mol wt 26  kDa
packaging   pkg of 10 μg
storage condition   avoid repeated freeze/thaw cycles
impurities   Endotoxin, tested
color   white
solubility   water: soluble 0.100 mL, clear, colorless
suitability   cell culture tested
UniProt accession no.   P12643
storage temp.   −20°C
Gene Information   human ... BMP2(650)

Description

Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 chondrogenic cells.

Physical form

Lyophilized from a 0.2 μm filtered buffered solution.

Biochem/physiol Actions

Cellular responses to BMP-2 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. BMPs stimulate angiogenesis by inducing the production of VEGF-A by osteoblasts. Human, mouse, and rat BMP-2 demonstrate 100% homology.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
104 °F
Flash Point(C) 
40 °C

Request a Serum Sample

Cell Culture Guide
Protocols & Articles

Related Content

Cell Culture Troubleshooting Guide

Cell culture has become one of the most fundamental techniques for modeling biological systems, and is of increasing importance in the biotechnology and pharmaceutical sectors as well as an essential...
Keywords: Antibiotics, Apoptosis, Cell attachment, Cell culture, Cryopreservation, Filtration, Growth factors, Pharmaceutical, Phase transitions

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?