• USA Home
  • B2134 - 2-Bromo-α-ergocryptine methanesulfonate salt

EMAIL THIS PAGE TO A FRIEND
B2134 Sigma-Aldrich

2-Bromo-α-ergocryptine methanesulfonate salt

solid

Synonym: (+)-2-Bromo-12′-hydroxy-2′-(1-methylethyl)-5′-(2-methylpropyl)ergotaman-3′,6′-18-trione methanesulfonate salt, (+)-Bromocriptine methanesulfonate salt, Bromocriptine mesylate salt

  • CAS Number 22260-51-1

  • Empirical Formula (Hill Notation) C32H40BrN5O5 · CH4SO3

  • Molecular Weight 750.70

  •  Beilstein/REAXYS Number 4115238

  •  EC Number 244-881-1

  •  MDL number MFCD00069218

  •  PubChem Substance ID 24277885

Purchase

Properties

Related Categories Agonists, B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents,
InChI Key   NOJMTMIRQRDZMT-NEKRQHSLSA-N
form   solid
optical activity   [α]20/D +95°, c = 1 in methanol: methylene chloride (1:1)(lit.)
color   white
solubility   H2O: 0.8 mg/mL
  ethanol: 23 mg/mL
storage temp.   2-8°C
Gene Information   human ... DRD2(1813), DRD3(1814), PRL(5617)

Description

Application

2-Bromo-α-ergocryptine methanesulfonate salt has been used:
• as D2 agonist in bird zebra finches
• for Prl secretion inhibitor in mice
• for the inhibition of motility in planaria worm

Biochem/physiol Actions

Bromocriptine is an ergot alkaloid and a dopamine D2 receptor agonist. It is prescribed for Parkinson′s disorder, hyperprolactinemia and galactorrhoea. It modulates β cells of the pancreas from insulin hypersecretion and improves the metabolic profile in type 2 diabetes patients with obesity. It also modulates glutamate release by glutamate transporter,GLT-1.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
KE1595000

Documents

Certificate of Analysis

Please Enter a Lot Number

Certificate of Origin

Please Enter a Lot Number

Making Headway

Milli-Q® Water Purification Solutions
Protocols & Articles

Related Content

Carcinogen Selector - Reproductive System - Uterus

The Carcinogen Selector gives researchers the ability to select carcinogens by the mouse organs that they promote cancer in. The tool includes over 750 carcinogens that target 35 specific organs acro...
Keywords: Cancer, Carcinogens, Respiratory

Carcinogen Selector - Reproductive System

From our library of Related Content, Sigma-Aldrich presents Carcinogen Selector - Reproductive System
Keywords: Cancer, Carcinogens, Respiratory

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?