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B2629 Sigma-Aldrich

Betaine

≥98% (perchloric acid titration)

Synonym: (Carboxymethyl)trimethylammonium inner salt, Oxyneurine, Trimethylglycine

  • CAS Number 107-43-7

  • Linear Formula (CH3)3N+CH2COO-

  • Molecular Weight 117.15

  •  Beilstein Registry Number 3537113

  •  EC Number 203-490-6

  •  MDL number MFCD00012123

  •  PubChem Substance ID 24891663

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Description

Packaging

1 kg in poly bottle

50, 100 g in poly bottle

Application

Betaine has been used to study the effects of antioxidants on regrowth from cryopreservation.

Biochem/physiol Actions

Apart from betaine taking part in transmethylation, it acts as an organic osmolyte in protecting cells under stress. This is being significantly observed in plants and microorganisms. Betaine is also known to increase the levels of S-adenosylmethionine and thus this might reduce the effects of hepatic steatosis.

End-product of oxidative metabolism of choline, betaine is a general methyl donor, in particular in a minor pathway of methionine biosynthesis. It is used to treat homocystinuria, which is a defect in the major pathway of methionine biosynthesis.

General description

Betaine is a quaternary ammonium zwitterion, extensively present in animals, plants and microorganisms. It also forms a good dietary source as it is found in wheat, spinach, shellfish and sugar beets. Betaine is a methyl derivative of the amino acid glycine. It is known by different names such as trimethylglycine, glycine betaine, lycine and oxyneurine.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. B2629.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DS5900000
Protocols & Articles
Peer-Reviewed Papers
15

References

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