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B2805 Sigma-Aldrich

Bone Morphogenetic Protein 6 human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, cell culture tested

Synonym: BMP-6

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Properties

Related Categories BMPs and Receptors, Cell Biology, Cell Culture, Cell Signaling and Neuroscience, Cytokines and Growth Factors,
biological source   human
recombinant   expressed in NSO cells
assay   >95% (SDS-PAGE)
form   lyophilized powder
potency   0.05-0.15 μg/mL ED50
mol wt   mol wt 30–38  kDa
packaging   pkg of 20 μg
storage condition   avoid repeated freeze/thaw cycles
impurities   endotoxin, tested
suitability   cell culture tested
UniProt accession no.   P22004
storage temp.   −20°C
Gene Information   human ... BMP6(654)

Description

Analysis Note

The biological activity is measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells.

Physical form

Lyophilized from 200 ul 0.2 μm filtered solution in 40% acetonitrile, 0.1% trifluoroacetic acid containing 50ug bovine serum albumin per 1 ug as a carrier protein.

Biochem/physiol Actions

Cellular responses to BMP-6 are mediated by the formation of hetero-oligomeric complexes of type I and type II serine/threonine kinase receptors. Mature human and murine BMP-6 demonstrates 96% homology.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


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Cell Culture Guide
Protocols & Articles

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Peer-Reviewed Papers
15

References

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