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B3383 Sigma-Aldrich

Benzidine dihydrochloride

≥99% (titration)

Synonym: 4,4′-Diaminobiphenyl dihydrochloride

  • CAS Number 531-85-1

  • Empirical Formula (Hill Notation) C12H12N2 · 2HCl

  • Molecular Weight 257.16

  •  Beilstein/REAXYS Number 3914846

  •  EC Number 208-519-6

  •  MDL number MFCD00040389

  •  PubChem Substance ID 24891713

  •  NACRES NA.25

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Properties

Related Categories B, Cell Biology, Hematology and Histology, Stains & Dyes, A to Z, Stains and Dyes More...
Quality Level   200
assay   ≥99% (titration)
SMILES string   Cl[H].Cl[H].Nc1ccc(cc1)-c2ccc(N)cc2
InChI   1S/C12H12N2.2ClH/c13-11-5-1-9(2-6-11)10-3-7-12(14)8-4-10;;/h1-8H,13-14H2;2*1H
InChI key   RUAXWVDEYJEWRY-UHFFFAOYSA-N

Description

Application

Benzidine (4,4′-Diaminobiphenyl) is an environmental genotoxin that posses increased risks of cancer to exposed people. Benzidine may be used as a reference material in procedures that analyze for benzidine. Benzidine can be used in studies on its mechanisms of genotoxicity.

Biochem/physiol Actions

Tumor initiator in mammary glands of experimental animal.

Warning

Cancer suspect agent.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
WGK 3
RTECS 
DD0600000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

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Peer-Reviewed Papers
15

References

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