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Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride

trypsin substrate

Synonym: BANA, Nα-Benzoyl-DL-arginine-2-naphthylamide hydrochloride

  • CAS Number 913-04-2

  • Empirical Formula (Hill Notation) C23H25N5O2 · HCl

  • Molecular Weight 439.94

  •  Beilstein/REAXYS Number 3823291

  •  EC Number 213-015-4

  •  MDL number MFCD00038940

  •  PubChem Substance ID 24891699

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Description

Application

Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride has been used as a substrate in the BANA test to evaluate the inhibitory activity of stefin. It has also been used as a substrate for the determination of Ki values of inhibitors toward trypsin.

Biochem/physiol Actions

Nα-Benzoyl-DL-arginine β-naphthylamide hydrochloride (BANA) helps to determine the activities of cathepsin B and papain. BANA test is also useful in identifying the number of periodontal sites with periodontal pathogens. Presence of volatile sulfur compounds (VSCs), synthesized by oral bacteria in dental plaque or tongue coating can be colorimetrically confirmed by their ability to hydrolyze N-benzoyl-DL-arginine-2-naphthylamide.

Substrates

A chromogenic substrate for trypsin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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