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B4894 Sigma-Aldrich

Benzyl 2-acetamido-2-deoxy-α-D-galactopyranoside

O-glycosylation inhibitor

Synonym: α-D-GalNAc-1→OCH2Ph, Benzyl N-acetyl-α-D-galactosaminide, Benzyl-α-GalNAc, GalNAc α-O-benzyl, GalNAc-O-bn

  • CAS Number 3554-93-6

  • Empirical Formula (Hill Notation) C15H21NO6

  • Molecular Weight 311.33

  •  MDL number MFCD00057920

  •  PubChem Substance ID 24891802

  •  NACRES NA.25

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C, Monosaccharide More...
Quality Level   100
assay   ≥97% (TLC)
form   powder
mp   204-208  °C
solubility   methanol: soluble 10 mg/mL, clear
storage temp.   −20°C
SMILES string   CC(=O)NC1C(O)C(O)C(CO)OC1OCc2ccccc2
InChI   1S/C15H21NO6/c1-9(18)16-12-14(20)13(19)11(7-17)22-15(12)21-8-10-5-3-2-4-6-10/h2-6,11-15,17,19-20H,7-8H2,1H3,(H,16,18)
InChI key   SKOZFDIGKDPQBO-UHFFFAOYSA-N

Description

Packaging

100, 500 mg in poly bottle

25 mg in glass insert

Biochem/physiol Actions

Benzyl-N-acetyl-α-galactosaminide inhibits glycosyltransferase incorporation of glucosamine into O-glycans. Suppresses mucin biosynthesis and inhibits MUC1 expression in breast cancer cell line MDF-7.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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