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B5438 Sigma-Aldrich

Balsalazide disodium salt hydrate

Synonym: 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate

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Properties

Related Categories Antioxidant and Free Radical Scavengers, Antioxidants and Cytoprotectants, Cancer Research, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥99% (HPLC)
storage temp.   2-8°C
SMILES string   O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
InChI   1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
InChI key   ZZZXQZHSFPVNCR-HVARVCSCSA-L

Description

Packaging

25 mg in poly bottle

Biochem/physiol Actions

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
nwg

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
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