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BM0013 Sigma-Aldrich

BMS-281384 bis-HCl

≥98% (HPLC)

Synonym: 4-[[(3-Chloro-4-methoxyphenyl)methyl]amino]-1-ethyl-N-(4-pyridinylmethyl)-1H-pyrazolo[3,4-b]pyridine-5-carboxamide bis-HCl

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Properties

Related Categories B, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   100
assay   ≥98% (HPLC)
form   powder
color   white to beige
solubility   DMSO: 2 mg/mL, clear (warmed)
storage temp.   room temp
SMILES string   [H]Cl.[H]Cl.ClC1=C(OC)C=CC(CNC2=C(C=NN3CC)C3=NC=C2C(NCC4=CC=NC=C4)=O)=C1

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

BMS-281384 is a selective and potent phosphodiesterase 5 (PDE 5) inhibitor. BMS-281384 was found to have an IC50 value of 0.8 nM for PDE5 and 47 to 9200-fold selective over other PDEs 1-6.

Features and Benefits

BMS-281384 is available through a partnership between Sigma Life Science and Bristol-Myers Squibb (BMS). To learn more and view other BMS compounds, visit sigma.com/BMS.

Legal Information

Sold for research purposes only under agreement from BMS.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

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