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C111P0-HH Sigma-Aldrich

DMT-dC(bz) Pharmadite®

Synonym: DMT-dC(bz) Phosphoramidite, N-benzoyl-5′-O-[bis(4-methoxyphenyl)phenylmethyl]-2′-deoxycytidine, 3′-[2-cyanoethyl N,N-?bis(1-methylethyl)phosphoramidite]

  • Empirical Formula (Hill Notation) C46H52N5O8P

  • Molecular Weight 833.91

  •  MDL number MFCD00036315

  •  PubChem Substance ID 329774857

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Properties

Quality Level   ELITE
biological source   non-animal source (no BSE/TSE risk)
InChI Key   PGTNFMKLGRFZDX-SALLYJDFSA-N
type   for DNA synthesis
product line   Proligo Reagents
assay   ≥99.5% (reversed phase HPLC)
  >99.5% (31P-NMR)
  conforms (1H-NMR)
  conforms (LC/MS)
form   powder or granules
packaging   pkg of (please inquire)
application(s)   oligo synthesis: suitable
impurities   >= 170ppm, none detected (S/N <2.5)
  ≤0.1% P(III) 100-169ppm (31P-NMR)
  ≤0.1% single unspecified Imprity (reversed phase HPLC)
  ≤0.3% dC2 (reversed phase HPLC, DMT-dC(bz) cyanoethyl-H-posphonate)
  ≤0.3% dC3 (reversed phase HPLC, DMT-dC(bz) phosphoramidate)
  ≤0.3% dC5 (reversed phase HPLC, O3′-Benzoyl-O5′-DMT-dC(bz))
  ≤0.30 wt. % water content (Karl Fischer)
  ≤0.5% P(V) -25-99ppm (31P-NMR)
  ≤3.0 wt. % residual solvent content
color   white to off-white
solubility   soluble, clear
nucleoside profile   base: cytidine
base protecting group: benzoyl
5' protecting group: DMT
deprotection: standard
storage temp.   2-8°C

Description

Legal Information

Pharmadite is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Protocols & Articles
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