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C1145 Sigma-Aldrich

Cholesterol–PEG 600

Synonym: Cholesterol, water soluble from sheep, Cholesteryl-polyethylene glycol 600 sebacate, Polyethylene glycol 600 mono(cholesteryl) ether sebacate, Polyoxyethyl-cholesteryl sebacate

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, C-CH, Cell Biology,
Quality Level   200
extent of labeling   ≥20% cholesterol
color   light yellow
solubility   H2O: 60 mg/mL
shipped in   dry ice
storage temp.   −20°C

Description

General description

Cholesterol is one of the important constituent of all membranes. It is made up of a hydrophobic, planar, a polar hydroxyl group, fused-ring nucleus and a short hydrocarbon tail.

Application

Cholesterol-PEG 600 has been used to evaluate its ability to induce apoptosis in vascular smooth muscle cells. It has also been used to restore cholesterol following depletion by methyl β-cyclodextrin.

Packaging

1, 5 g in serum bottle

250, 500 mg in serum bottle

Biochem/physiol Actions

Cholesterol acts as an antecedent of steroid hormones. It plays a key role in fetal growth and in brain development.

Physical form

semisolid to solid

Preparation Note

Prepared by method of Proksch, G.J., and Bonderman, D.P., Clin. Chem., 24, 1924 (1978).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
FZ8400000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Discover Bioactive Small Molecules for Lipid Signaling Research

Within mammalian cells, a multitude of lipid compounds are found with a variety of cellular functions, including structural components of cell membranes and as second messengers in cell signaling pat...
Keywords: Absorption, Atomic absorption spectroscopy, Cancer, Cardiovascular, Cell signaling, Diabetes, Digestions, Diseases, Growth factors, Hormones, Inflammation, Lipid Metabolism, Lipid signaling, Metabolism

Polyethylene Glycol (PEG) Selection Guide

Poly(ethylene glycol) (PEG) is a synthetic, hydrophilic, biocompatible polymer with widespread use in biomedical and other applications. PEGs are synthesized using a ring-opening polymerization of et...
Keywords: Adhesion, Bacterial conjugations, Click chemistry, Molecular biology, PEGylations, Polymerization reactions, Ring-opening polymerization

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Peer-Reviewed Papers
15

References

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