C1251 Sigma-Aldrich

(+)-Catechin hydrate

≥98% (HPLC), powder

Synonym: (+)-Cyanidol-3, (2R,3S)-2-(3,4-Dihydroxyphenyl)-3,4-dihydro-1(2H)-benzopyran-3,5,7-triol

  • CAS Number 225937-10-0

  • Empirical Formula (Hill Notation) C15H14O6 · xH2O

  • Molecular Weight 290.27 (anhydrous basis)

  •  Beilstein/REAXYS Number 3595244

  •  EC Number 205-825-1

  •  MDL number MFCD00150865

  •  PubChem Substance ID 57653982



General description

Catechins are phytochemicals, richly present in black grapes, peaches, strawberries and broad beans. Catechins occur in various forms such as catechins, epicatechin, epicatechin gallate, epigallocatechin and epigallocatechin gallate.


(+)-Catechin hydrate has been used:
• as a polyphenol standard in the determination of total polyphenols in the by-products of red wine
• as an additive to study its effects on in vitro methane production and substrate degradation in a triple-fed batch approach
• as a substrate to determine the activity of pure L. plantarum CECT 748T 14 recombinant tannase on catechin


5, 10 g in poly bottle

Biochem/physiol Actions

An antioxidant flavonoid of plant origin; a free radical scavenger, preventing free radical-mediated damage in a variety of biological systems. For example, at physiological pH catechin suppressed DNA strand breaks by hydroxyl radicals. It has also been shown to prevent human plasma oxidation. It delayed the consumption of endogenous lipid-soluble antioxidants and inhibited lipid oxidation. Catechin may also function as an inhibitor of fatty acid synthase.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Target organs 
Respiratory system
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles


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