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C1276 Sigma-Aldrich

L-Cysteine hydrochloride

anhydrous, ≥98% (TLC)

  • CAS Number 52-89-1

  • Linear Formula HSCH2CH(NH2)COOH · HCl

  • Molecular Weight 157.62

  •  Beilstein/REAXYS Number 3560277

  •  EC Number 200-157-7

  •  MDL number MFCD00064553

  •  PubChem Substance ID 24892395

  •  NACRES NA.32

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Properties

Related Categories Amino acids, Cell Biology, Cell Signaling and Neuroscience, Excitatory Amino Acids, Functional Foods,
Quality Level   100
grade   anhydrous
assay   ≥98% (TLC)
form   powder
application(s)   UHPLC: suitable
color   white
mp   174.1-174.7 °C
solubility   H2O: 50 mg/mL, clear, colorless
SMILES string   Cl[H].N[C@@H](CS)C(O)=O
InChI   1S/C3H7NO2S.ClH/c4-2(1-7)3(5)6;/h2,7H,1,4H2,(H,5,6);1H/t2-;/m0./s1
InChI key   IFQSXNOEEPCSLW-DKWTVANSSA-N
Gene Information   human ... AMPA 1(2890), GRIA2(2891), GRIA3(2892), GRIA4(2893), GRIN1(2902), GRIN2A(2903), GRIN2B(2904), GRIN2C(2905), GRIN2D(2906), GRIN3A(116443), GRIN3B(116444), GRINA(2907)
mouse ... AMPA 1(14799), GRIA2(14800), GRIA3(53623), GRIA4(14802), GRIN1(14810), GRIN2A(14811), GRIN2B(14812), GRIN2C(14813), GRIN2D(14814), GRIN3A(242443), GRIN3B(170483), GRINA(66168)
rat ... AMPA 1(50592), GRIA2(29627), GRIA3(29628), GRIA4(29629), GRIN1(24408), GRIN2A(24409), GRIN2B(24410), GRIN2C(24411), GRIN2D(24412), GRIN3A(191573), GRIN3B(170796), GRINA(266668)

Description

Application

L-Cysteine hydrochloride has been used as a supplement in media to study the metabolic and sleep phenotypes of Drosophila melanogaster. It has also been used as one of the reagents for cell dissociation and single cell collection.

Biochem/physiol Actions

Cysteine (Cys) is a functional sulfur-containing aminoacid that regulates metabolism for growth, reproduction and immunity. It provides the disulfide linkage in proteins and is involved in the transport of sulfur. Cysteine is involved in the formation of hydrogen sulfide that functions as a signaling molecule. Cys residues are present at the catalytic sites of various enzymes.

NMDA glutamatergic receptor agonist that is also an agonist at AMPA glutamatergic receptors at high concentrations.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
HA2275000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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