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  • C1368 - Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide

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C1368 Sigma-Aldrich

Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide

≥98% (HPLC), solid

Synonym: Aurora Kinase Inhibitor III

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ, Cell Biology, Cell Signaling and Neuroscience,
assay   ≥98% (HPLC)
form   solid
color   white
solubility   H2O: <2 mg/mL
  DMSO: >7 mg/mL
storage temp.   2-8°C
SMILES string   FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
InChI   1S/C21H18F3N5O/c22-21(23,24)14-3-1-4-15(11-14)26-18-9-10-25-20(29-18)28-17-6-2-5-16(12-17)27-19(30)13-7-8-13/h1-6,9-13H,7-8H2,(H,27,30)(H2,25,26,28,29)
InChI key   RDTDWGQDFJPTPD-UHFFFAOYSA-N

Description

Packaging

1, 5 mg in glass bottle

Biochem/physiol Actions

ATP-competitive Aurora A kinase inhibitor with IC50 = 42 nM

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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