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C1613 Sigma-Aldrich

Carbenicillin

Ready Made Solution, 100 mg/mL in ethanol/water, 0.2 μm filtered

Synonym: α-Carboxybenzylpenicillin solution

  • Empirical Formula (Hill Notation) C17H18N2O6S

  • Molecular Weight 378.40

  •  MDL number MFCD00242604

  •  PubChem Substance ID 24892425

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Properties

Related Categories A - K, Antibacterial, Antibiotic Ready Made Solutions, Antibiotics, Antibiotics A to Z,
InChI Key   FPPNZSSZRUTDAP-UWFZAAFLSA-N
sterility   0.2 μm filtered
form   liquid
concentration   100 mg/mL in ethanol/water
solubility   H2O: 100 mg/mL
  ethanol: 100 mg/mL
suitability   suitable for testing specifications (Bacteriostatic (cell type) E. Coli DH5a, result: pass)
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
shipped in   wet ice
storage temp.   −20°C

Description

Application

Carbenicillin is used for selection of Ampicillin-resistant transformed cells. It is used to study the role of penicillin-sensitive transpeptidases in the process cell wall biosynthesis.

Biochem/physiol Actions

Carbenicillin is an ampicillin analog with structure related to benzyl penicillin. It is effective against Gram-negative bacteria and exhibits limited activity against Gram-positive bacteria. Carbenicillin binds and inhibits the enzymes involved in the synthesis of bacterial cell wall. Since carbenicillin is less sensitive to β-lactamases than ampicillin, it is effective against ampicillin-resistant bacteria. It has superior stability at low pH and acts as a selection agent. Effective concentration of carbenicillin: 50 to 100 μg/ml.

Packaging

1 mL in glass bottle

General description

Chemical structure: ß-lactam

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN1170 - class 3 - PG 3 - Ethanol, solution
WGK Germany 
2
Flash Point(F) 
104 °F
Flash Point(C) 
40 °C
Protocols & Articles

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Peer-Reviewed Papers
15

References

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