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C1619 Sigma-Aldrich

CGS-9343B

≥98% (HPLC), powder

Synonym: 1,3-Dihydro-1-[1-[(4-methyl-4H,6H-pyrrolo[1,2-a][4,1]- benzoxazepin-4-yl)methyl]-4-piperidinyl]-2H-benzimidazol-2-one maleate, CGS9343B, KW-5617, Zaldaride maleate

  • CAS Number 109826-27-9

  • Empirical Formula (Hill Notation) C26H28N4O2 · C4H4O4

  • Molecular Weight 544.60

  •  MDL number MFCD04113002

  •  PubChem Substance ID 329774899

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH, Calcium Antagonists,
InChI Key   NGODOSILXOFQPH-BTJKTKAUSA-N
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: >10 mg/mL
originator   Novartis
storage temp.   2-8°C

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

CGS-9343B is a selective calmodulin antagonist with minimal protein kinase C or antidopaminergic activity. CGS-9343B is a potent inhibitor of calmodulin-activated (Type I) phosphodiesterase activity with IC50 in the nanomolar range.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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