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C2389 Sigma-Aldrich

Cerulenin

≥98% (HPLC), from Cephalosporium caerulens

Synonym: (2R,3S,E,E)-2,3-Epoxy-4-oxo-7,10-dodecadienamide

  • CAS Number 17397-89-6

  • Empirical Formula (Hill Notation) C12H17NO3

  • Molecular Weight 223.27

  •  Beilstein Registry Number 4140423

  •  EC Number 241-424-8

  •  MDL number MFCD00083595

  •  PubChem Substance ID 24892323

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Description

Biochem/physiol Actions

Cerulenin, an antibiotic and antifungal, is an inhibitor of fatty acid biosynthesis; in vitro inhibition of HIV-1 proteinase.

Packaging

5, 10, 50 mg in glass bottle

General description

Chemical structure: fatty acid derivative

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
JR1670000

Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Cholesterol Biosynthesis Regulation

The amount of cholesterol that is synthesized in the liver is tightly regulated by dietary cholesterol levels. When dietary intake of cholesterol is high, synthesis is decreased and when dietary inta...
BioFiles 2007, 2.7, 6.
Keywords: Gene expression, Transcription

Discover Bioactive Small Molecules for Lipid Signaling Research

Within mammalian cells, a multitude of lipid compounds are found with a variety of cellular functions, including structural components of cell membranes and as second messengers in cell signaling pat...
Keywords: Absorption, Atomic absorption spectroscopy, Cancer, Cardiovascular, Cell signaling, Diabetes, Digestions, Diseases, Growth factors, Hormones, Inflammation, Lipid Metabolism, Lipid signaling, Metabolism

Fatty Acid Synthesis and Metabolism in Cancer Cells

Proliferatively active cells require fatty acids for functions such as membrane generation, protein modification, and bioenergetic requirements. These fatty acids are derived either from dietary sour...
Keywords: Apoptosis, Biofiles, Cancer, Carboxylations, Catalysis, Citric Acid Cycle, Gene expression, Glycolysis, Metabolism, Oxidations, PAGE, Phosphorylations

Peer-Reviewed Papers
15

References

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