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C3292 Sigma-Aldrich

Cholesterol

≥95% (GC), powder, Ash, free

Synonym: 3β-Hydroxy-5-cholestene, 5-Cholesten-3β-ol

  • CAS Number 57-88-5

  • Empirical Formula (Hill Notation) C27H46O

  • Molecular Weight 386.65

  •  Beilstein/REAXYS Number 1915888

  •  EC Number 200-353-2

  •  MDL number MFCD00003646

  •  PubChem Substance ID 24892601

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Properties

Related Categories Biochemicals and Reagents, Cell Biology, Cell Signaling and Neuroscience, Cholesterol, Cholesterol and Cholesterol Metabolism,
assay   ≥95% (GC)
form   powder
impurities   Ash, free
color   white
bp   360 °C (lit.)
mp   147-149 °C (lit.)
solubility   water: soluble 0.00003 g/L at 20 °C
density   1.067 g/mL at 25 °C (lit.)
shipped in   ambient
storage temp.   2-8°C
SMILES string   CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CC=C4C[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C
InChI   1S/C27H46O/c1-18(2)7-6-8-19(3)23-11-12-24-22-10-9-20-17-21(28)13-15-26(20,4)25(22)14-16-27(23,24)5/h9,18-19,21-25,28H,6-8,10-17H2,1-5H3/t19-,21+,22+,23-,24+,25+,26+,27-/m1/s1
InChI key   HVYWMOMLDIMFJA-DPAQBDIFSA-N
Gene Information   human ... POLA1(5422), TOP2A(7153)
rat ... Ar(24208), Polb(29240)

Description

Biochem/physiol Actions

Major component of all biological membranes; ~25% of total brain lipid is cholesterol.

Preparation Note

Precipitated from alcohol

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
FZ8400000
Protocols & Articles

Articles

Cholesterol Biosynthesis

Cholesterol levels in the body come from two sources, dietary intake and biosynthesis. The majority of cholesterol utilized by healthy adults is synthesized in the liver, which produces ~70% of the t...
BioFiles 2007, 2.7, 3.
Keywords: Catalysis, Decarboxylations, Metabolic Pathways, Oxidations, PAGE, Phosphorylations, Reductions

Peer-Reviewed Papers
15

References

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C8667 Cholesterol, Sigma Grade, ≥99%

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