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C3366 Sigma-Aldrich

Anti-CXCR5 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

Synonym: Anti-CXC Chemokine Receptor 5

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Properties

Related Categories Alphabetical Index, Antibodies, Antibodies against Proteins/Bioactives/Markers/Receptors for Stem Cell Biology, Antibodies for Cell Biology, Antibodies to Chemokine Receptors,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 5 μg/mL using human lymph node, B-cell lymphoma
species reactivity   human
form   buffered aqueous solution
shipped in   dry ice
storage temp.   −20°C
antibody form   affinity isolated antibody
antibody product type   primary antibodies
UniProt accession no.   P32302
Gene Information   human ... CXCR5(643)
mouse ... Cxcr5(12145)
rat ... Cxcr5(29363)

Description

Immunogen

synthetic peptide corresponding to the C-terminus of human CXC chemokine receptor 5 (CXCR5), conjugated to KLH. The immunizing peptide has 94% homology with the rat gene and 100% homology with the mouse gene.

Physical form

Solution in phosphate buffered saline, pH 7.7, containing 0.01% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

CXCR5 is a multi-pass membrane protein expressed in mature B cells. It binds to B-lymphocyte chemoattractant and regulates the migration of B cells. The expression of CXCR5 is important for CD4 T cell-mediated humoral immune responses.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis

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Milli-Q® Water Purification Solutions
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy

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Peer-Reviewed Papers
15

References

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