• USA Home
  • C3678 - Anti-Pan Cadherin antibody produced in rabbit

C3678 Sigma-Aldrich

Anti-Pan Cadherin antibody produced in rabbit

whole antiserum



Related Categories Alphabetical Index, Antibodies, Antibodies against Adhesion, Attachment, and Matrix Factors, Antibodies against Adhesion/Attachment/Matrix Factors, Antibodies for Cell Biology,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:1,000 using protease-digested animal heart sections
  indirect immunofluorescence: 1:100 using cultured MDBK cells
  western blot: 1:200
species reactivity   chicken, human, cat, rabbit
mol wt   antigen 135 kDa
shipped in   dry ice
storage temp.   −20°C
antibody form   whole antiserum
antibody product type   primary antibodies
contains   15 mM sodium azide
UniProt accession no.   P19022
Gene Information   chicken ... CDH2(414745)


General description

Cadherins are glycoprotein receptors that regulate Ca2+-dependant adhesion in cells. Cadherins are associated with adherens junctions and are mainly involved in morphogenesis of cells and tissues. P-cadherin is expressed in epithelial cells and its over-expression has been associated with breast cancer metastasis and invasion . Anti-Pan Cadherin antibody is specific for cadherins in a wide range of organisms including chickens, rabbits and rats.


The epitope recognized by the antibody is shared by a wide variety of organisms.


Synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids) coupled with glutaraldehyde to keyhole limpet hemocyanin (KLH).


Anti-Pan Cadherin antibody is suitable for use in confocal immunofluorescence using rat ventricular myocytes and western blot (1:200). The antibody may also be used for indirect immunofluorescence (1:100 using cultured MDBK cells) and immunohistochemistry (in formalin-fixed, paraffin-embedded sections or at 1:1,000 dilutions using protease-digested animal heart sections). Additionally, the product can be used in indirect immunoblot (135 kDa band in chicken or rabbit heart extracts), immunoperoxidase and immunoelectron-microscopy assays.

May be used for the detection of members of the cadherin family or genetically engineered proteins containing the C-terminal cadherin tail, and for demonstration of adherens type cell-cell junctions regardless of their cadherin type.


Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 


Certificate of Analysis (COA)

Please Enter a Lot Number
Protocols & Articles


Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
Keywords: Affinity chromatography, Centrifugation, Chromatography, Digestions, Direct immunofluorescence, Gene expression, High performance liquid chromatography, Immunofluorescence, Ion Exchange, Microscopy, Precipitation, Purification, Rheumatology, Scanning electron microscopy


Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detection methods, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

Related Content

Antibody Explorer | Buy Primary Antibodies & Secondary Antibodies

Primary, Secondary and Recombinant Monoclonal Antibodies Providing highly cited primary and secondary antibodies, we have you covered for your ELISA, western blot, immunohistochemistry or other assay...
Keywords: Alzheimer Disease, Cancer, Chromatin immunoprecipitation, Diagnostic, Enzyme-linked immunosorbent assay, Flow cytometry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry, Neuroscience, Western blot

Peer-Reviewed Papers


Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?