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C3915 Sigma

Colchicine

BioReagent, plant cell culture tested, ≥95% (HPLC)

Synonym: (S)-N-(5,6,7,9-Tetrahydro-1,2,3,10-tetramethoxy-9-oxobenzo[a]heptalen-7-yl)acetamide

  • CAS Number 64-86-8

  • Empirical Formula (Hill Notation) C22H25NO6

  • Molecular Weight 399.44

  •  Beilstein Registry Number 2228813

  •  EC Number 200-598-5

  •  MDL number MFCD00078484

  •  PubChem Substance ID 24892656

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Properties

InChI Key   IAKHMKGGTNLKSZ-INIZCTEOSA-N
product line   BioReagent
assay   ≥95% (HPLC)
mp   150-160 °C (dec.)(lit.)
suitability   plant cell culture tested
Featured Industry   Agriculture
Gene Information   human ... ABCB1(5243), CYP3A4(1576)
mouse ... Abcb1a(18671), Abcb1b(18669)

Description

Packaging

1, 5 g in glass bottle

500 mg in glass bottle

Preparation Note

Preparation and Use

Biochem/physiol Actions

Colchicine is an inhibitor of microtubule polymerization which blocks chromosome segregation during meiosis. Consequently, Colchicine is used to induce polyploidy (tetraploid) in plant cells.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1544PSN1 6.1 / PGI
WGK Germany 
3
RTECS 
GH0700000
Protocols & Articles

Articles

Using Global Reach to Source and Deliver Critical Plant Breeding Chemicals

For many crops, colchicine is used to produce doubled haploids, enabling homozygosity in a single generation. When used, this process enables seed development companies to deliver better-performing v...
Keywords: Agriculture

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Peer-Reviewed Papers
15

References

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