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C4024 Sigma

Carbamazepine

powder

Synonym: 5H-Dibenz[b,f]azepine-5-carboxamide

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Benzodiazepines and Anxiolytics, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, C-CH,
InChI Key   FFGPTBGBLSHEPO-UHFFFAOYSA-N
form   powder
mp   191-192 °C(lit.)
solubility   45% (w/v) aq 2-hydroxypropyl-β-cyclodextrin: 29 mg/mL
  H2O: insoluble
  ethanol: soluble
  propylene glycol: soluble
originator   Novartis
storage temp.   2-8°C
Gene Information   human ... BZRAP1(9256), GABRA1(2554), GABRA2(2555), GABRA3(2556), GABRA4(2557), GABRA5(2558), GABRA6(2559), GABRB1(2560), GABRB2(2561), GABRB3(2562), PRNP(5621), SCN5A(6331)
rat ... Scn2a1(24766), Scnn1a(25122), Scnn1g(24768), Slc6a1(79212)

Description

Biochem/physiol Actions

Anticonvulsant; ligand for the GABAA receptor benzodiazepine modulatory site. Sodium channel inhibitor.

Packaging

1, 5, 10, 25 g in glass bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

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Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
HN8225000
Protocols & Articles
Peer-Reviewed Papers
15

References

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