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  • C4106 - Anti-Caspase 8 antibody, Mouse monoclonal

C4106 Sigma

Anti-Caspase 8 antibody, Mouse monoclonal

clone CAS8, purified from hybridoma cell culture



Related Categories Alphabetical Index, Antibodies, Antibodies for Apoptosis, Antibodies for Cell Biology, Antibodies to Caspases,
species reactivity   human
application(s)   indirect ELISA: suitable
  microarray: suitable
  western blot: 5-10 μg/mL using whole extract of a HeLa cells mitochondrial preparation
clone   CAS8, monoclonal
concentration   ~2 mg/mL
antibody form   purified immunoglobulin
form   buffered aqueous solution
isotype   IgM
mol wt   antigen mol wt 53 kDa (additional bands may be seen at 33 and 10 kDa)
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... CASP8(841)
biological source   mouse
conjugate   unconjugated



recombinant human caspase 8.

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.


Monoclonal Anti-Caspase 8 is suitable for:
• indirect ELISA
• microarray
• western blot at a concentration of 5-10μg/mL using whole extract of a HeLa cells mitochondrial preparation

Biochem/physiol Actions

Caspases (Cysteine-requiring Aspartate protease) are a family of proteases. Caspase-8 and -10 are involved in death receptor mediated apoptosis.

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Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Western Blot Protocol | Immunoblotting Protocol

Western Blotting refers to the electrophoretic transfer of proteins from sodium dodecyl sulfate polyacrylamide gels to sheets of PVDF or nitrocellullose membrane, followed by immunodetection of prote...
Keywords: AGE, Buffers, Cell disruption, Detergents, Dialysis, Electroblotting, Electrophoresis, Enzyme activity, Gel electrophoresis, Immunoprecipitation, PAGE, Protein extraction, Purification, Sample preparations, Western blot

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