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C4124 Sigma-Aldrich

Chromium picolinate

≥98% (HPLC)

Synonym: Cr(pic)3, CrPic

  • CAS Number 14639-25-9

  • Empirical Formula (Hill Notation) C18H12CrN3O6

  • Molecular Weight 418.30

  •  MDL number MFCD00068715

  •  PubChem Substance ID 329775054

  •  NACRES NA.25

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Properties

Quality Level   100
biological source   synthetic
assay   ≥98% (HPLC)
loss   ≤5% loss on drying
storage temp.   room temp
SMILES string   O=C(O[Cr](OC(=O)c1ccccn1)OC(=O)c2ccccn2)c3ccccn3
InChI   1S/3C6H5NO2.Cr/c3*8-6(9)5-3-1-2-4-7-5;/h3*1-4H,(H,8,9);/q;;;+3/p-3
InChI key   CBDQOLKNTOMMTL-UHFFFAOYSA-K

Description

General description

Chromium picolinate is a supplemental or alternative medication for type 2 diabetes and an anti-diabetic mechanisms of CrPic in insulin-resistant 3T3-L1 adipocytes.

Application

Chromium picolinate (CrPic), a dietay supplement, may be used to study its potential as a modulator of glucose uptake and the activity of insulin. CrPic is used to study its effects on nuclear factor-κ B (NF-κB) and nuclear factor-E2-related factor-2 (Nrf2) pathways in animals.

Packaging

5, 25 g in poly bottle

Biochem/physiol Actions

Chromium picolinate (CrPic) is a supplemental or alternative medication for type 2 diabetes. Experimental evidence shows the effect of CrPic on glucose uptake through the activation of p38 MAPK. Chromium is thought to potentiate the action of insulin, leading to increased insulin sensitivity in type 2 diabetes.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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