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C4610 Sigma-Aldrich

Cytochrome P450 human

4A11 isozyme microsomes, with P450 Reductase, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4)

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Properties

recombinant   expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
packaging   vial of 0.5 nmol
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CYP4A11(1579)

Description

Biochem/physiol Actions

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

The CYP4A11 isoform catalyzes the ω-hydroxylation of lauric acid.

Physical form

Solution in 100 mM Tris-HCl buffer, pH 7.5.

Preparation Note

Microsomes containing human CYP4A11 and recombinant human NADPH-P450 reductase.

Safety & Documentation

Safety Information

WGK Germany 
1

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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