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C4735 Sigma-Aldrich

Cytochrome P450 human

2A6 isozyme microsomes, with P450 Reductase and cytochrome b5, recombinant, expressed in baculovirus infected insect cells (BTI-TN-5B1-4)

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Properties

recombinant   expressed in baculovirus infected insect cells (BTI-TN-5B1-4)
packaging   vial of 0.5 nmol
storage temp.   −70°C
Gene Information   human ... CYP2A6(1548)

Description

Biochem/physiol Actions

Catalyzes 7-hydroxylation of coumarin.

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

Physical form

Solution in 100 mM Tris-HCl buffer, pH 7.5.

Safety & Documentation

Safety Information

WGK Germany 
1

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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