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C5157 Sigma-Aldrich

Campesterol

~65%

Synonym: 24α-Methyl-5-cholesten-3β-ol, 24(R)-Ergost-5-en-3β-ol

  • CAS Number 474-62-4

  • Empirical Formula (Hill Notation) C28H48O

  • Molecular Weight 400.68

  •  Beilstein/REAXYS Number 3216975

  •  EC Number 207-484-4

  •  MDL number MFCD00010475

  •  PubChem Substance ID 24892762

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Properties

Related Categories Allium cepa (Onion), Allium sativum (Garlic), Aloe Vera, Armoracia rusticana (Horseradish), Biochemicals and Reagents,
Quality Level   200
biological source   Glycine max (soybean)
assay   ~65%
form   powder
shipped in   ambient
storage temp.   −20°C
SMILES string   [H][C@@]12CC=C3C[C@@H](O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)[C@H](CC[C@@]24[H])[C@H](C)CC[C@H](C)C(C)C
InChI   1S/C28H48O/c1-18(2)19(3)7-8-20(4)24-11-12-25-23-10-9-21-17-22(29)13-15-27(21,5)26(23)14-16-28(24,25)6/h9,18-20,22-26,29H,7-8,10-17H2,1-6H3/t19-,20+,22-,23-,24+,25-,26-,27-,28+/m0/s1
InChI key   SGNBVLSWZMBQTH-ZRUUVFCLSA-N

Description

Application

Campesterol was used as standard in GC and HPLC analysis of oil samples from plants.

Packaging

1, 5, 10 mg in glass bottle

Biochem/physiol Actions

Campesterol is a phytosterol, primarily found in nuts, fruits, legumes and seeds. Though an analogue of cholesterol, it is poorly absorbed in humans and competitively inhibits the absorption of cholesterol. Campesterol decreases the transcription of genes involved in cholesterol metabolism in hepatocytes and enterocytes and has positive impact in treatment of cardiovascular disease.

Quality

Appears ~98% by HPLC and GC, but has been shown by 13C-NMR to contain ~35% dihydrobrassicasterol (24β-methyl-5-cholesten-3β-ol; 24[S]-ergost-5-en-3β-ol).

Preparation Note

Campesterol yields clear, colorless to faint yellow solution in chloroform at 20 mg/ml.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

BACSMLS Online Plate Map

BACSMLS compounds are conveniently provided at 5µg per well, enough for multiple injections. These are high purity (>95%) compounds supplied in an economical, ready to use format. Compounds are arran...
Keywords: Metabolites

Blocking Absorption of Dietary Cholesterol

Dietary cholesterol is obtained from foods derived from animal sources that are rich in fat content. A healthy adult only needs to ingest about 30% of the daily cholesterol requirement. Obtaining mor...
BioFiles 2007, 2.7, 9.
Keywords: Absorption, Biofiles

GC Analysis of Sterols (Silylated Derivatives) in Olive Oil (Free Sterol Fraction) on SLB®-5ms after SPE using Discovery DSC-Si

From our library of Articles, Sigma-Aldrich presents GC Analysis of Sterols (Silylated Derivatives) in Olive Oil (Free Sterol Fraction) on SLB®-5ms after SPE using Discovery DSC-Si
Keywords: Agriculture, Calorimetry, Chromatography, Fractionation, Gas chromatography, Gas chromatography mass spectrometry, Mass selective detector, Mass spectrometry, Purification, Sample preparations, Saponifications, Silylations, Solid phase extractions

GC Analysis of Sterols in Soybean Oil on SAC™-5

From our library of Articles, Sigma-Aldrich presents GC Analysis of Sterols in Soybean Oil on SAC™-5
Keywords: Chromatography, Flame ionization detector, Gas chromatography, Purification, Size-exclusion chromatography

Peer-Reviewed Papers
15

References

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