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C5259 Sigma-Aldrich

Carbamyl-β-methylcholine chloride

≥99% (TLC), crystalline

Synonym: Bethanechol chloride

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Properties

Related Categories Agonists, Cell Biology, Cell Signaling and Neuroscience, Cholinergics, Neuroscience,
Quality Level   100
assay   ≥99% (TLC)
form   crystalline
color   white
solubility   H2O: 1.7 g/mL (stable for several days at 4°C.)
  ethanol: 80 mg/mL (stable for several days at 4°C.)
storage temp.   2-8°C
SMILES string   Cl.CC(C[N](C)(C)C)OC(N)=O
InChI   1S/C7H17N2O2.ClH/c1-6(11-7(8)10)5-9(2,3)4;/h6H,5H2,1-4H3,(H2,8,10);1H
InChI key   AIRHOJQHGLTTTB-UHFFFAOYSA-N

Description

Application

Carbamyl-β-methylcholine chloride has been used in western blotting and bactericidal assay. It has also been used in concentration-response studies with isolated atrial preparation.

Packaging

5, 100 g in poly bottle

Biochem/physiol Actions

Carbamyl-β-methylcholine has a selective action on urinary bladder and intestine. It induces smooth muscle tension in the bladder. Its main function is to induce detrusor muscle action, mediated by postganglionic parasympathetic effector cells. Nausea, flushing, sweating, abdominal cramps are some of the side effect caused by carbamyl-β-methylcholine.

Caution

Hygroscopic.

Substrates

Muscarinic acetylcholine receptor agonist that is not a substrate for acetylcholinesterase.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
BR5425000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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