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C5423 Sigma-Aldrich

Clenbuterol hydrochloride

≥95%

Synonym: 4-Amino-α-(t-butylaminomethyl)-3,5-dichlorobenzyl alcohol hydrochloride

  • CAS Number 21898-19-1

  • Empirical Formula (Hill Notation) C12H18Cl2N2O · HCl

  • Molecular Weight 313.65

  •  EC Number 244-643-7

  •  MDL number MFCD00083280

  •  PubChem Substance ID 24892782

  •  NACRES NA.77

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Properties

Related Categories Adrenergics, Adrenergics - Agonists, Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
Quality Level   200
assay   ≥95%
drug control   Home Office Schedule 4.2
storage temp.   2-8°C
SMILES string   Cl.CC(C)(C)NCC(O)c1cc(Cl)c(N)c(Cl)c1
InChI   1S/C12H18Cl2N2O.ClH/c1-12(2,3)16-6-10(17)7-4-8(13)11(15)9(14)5-7;/h4-5,10,16-17H,6,15H2,1-3H3;1H
InChI key   OPXKTCUYRHXSBK-UHFFFAOYSA-N
Gene Information   human ... ADRB2(154)

Description

Application

Clenbuterol hydrochloride has been used:
• as an agonist for β-adrenergic receptor (β-AR) from chick skeletal muscle
• to induce hypertrophic effects in masseter, digastric, and temporalis muscles of rat
• as a reference β-agonist standard in tandem mass spectrometry(MS-MS)

Biochem/physiol Actions

Clenbuterol hydrochloride is a β2-adrenoceptor agonist and bronchodilator. It is effective in improving peak expiratory flow rate (PEFR) in asthma patients. Clenbuterol is also a performance-enhancing drug as it stimulates the central nervous system and improves oxygen transport. Clenbuterol elicits cardio protective functionality in patients with dilated cardiomyopathy.

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
WGK 3
RTECS 
DN3180000
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

LC/MS Analysis of Clenbuterol In Plasma on Astec® CHIROBIOTIC® T with Phospholipid Removal using HybridSPE® Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS Analysis of Clenbuterol In Plasma on Astec® CHIROBIOTIC® T with Phospholipid Removal using HybridSPE® Phospholipid
Keywords: Chromatography, Clinical, Forensic, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Precipitation, Sample preparations, Solid phase extractions

Peer-Reviewed Papers
15

References

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