• USA Home
  • C5607 - Cytochrome P450 human

EMAIL THIS PAGE TO A FRIEND
C5607 Sigma-Aldrich

Cytochrome P450 human

2C19 Isozyme, with P450 Reductase, recombinant, expressed in E. coli

Purchase

Properties

recombinant   expressed in E. coli
shipped in   dry ice
storage temp.   −70°C
Gene Information   human ... CYP2C19(1557)

Description

Biochem/physiol Actions

Cytochrome P450 is a heterogeneous family of isozymes whose primary function is to oxidize small molecules, both as a function of intermediary metabolism (e.g., fatty acids) and to detoxify exogenous compounds (drugs or toxins). Some isoforms have narrow substrate specificity, while others are promiscuous.

Unit Definition

One unit will hydroxylate 1 nanomole of mephenytoin per minute at pH 7.4 at 37 °C.

Physical form

Solution in 20 mM potassium phosphate buffer, 1 mM EDTA, 0.1 mM DTT and 20% (v/v) glycerol, pH 7.4.

Other Notes

The product as supplied is stable for at least 18 months.

Safety & Documentation

Safety Information

WGK Germany 
1
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?