C5874 Sigma-Aldrich

Cidofovir hydrate

≥98% (HPLC)

Synonym: (S)-HPMPC; Cidovir, (S)-1-[3-hydroxy-2-(phosphonylmethoxy)propyl]cytosine, HPMPC, Vistide



Related Categories AIDS and Viral Research Reagents, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, CI-CZ,
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
  protect from light
solubility   deionized water: ≥5 mg/mL (warmed)
originator   Pfizer
storage temp.   room temp
SMILES string   O.NC1=NC(=O)N(C[C@@H](CO)OCP(O)(O)=O)C=C1
InChI   1S/C8H14N3O6P.H2O/c9-7-1-2-11(8(13)10-7)3-6(4-12)17-5-18(14,15)16;/h1-2,6,12H,3-5H2,(H2,9,10,13)(H2,14,15,16);1H2/t6-;/m0./s1



10, 50 mg in glass bottle

Biochem/physiol Actions

Selective inhibitor of viral DNA synthesis through the selective inhibition of viral DNA polymerase.

Features and Benefits

This compound is a featured product for ADME Tox research. Click here to discover more featured ADME Tox products. Learn more about bioactive small molecules for other areas of research at

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

GHS06  GHS06
Signal word 
Hazard statements 
Precautionary statements 
UN 2811 6.1 / PGIII
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
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What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
What is the solubility of Product C5874 (Cidofovir hydrate)?
Product C5874 (Cidofovir hydrate) is soluble at 22 mg/mL in water, with warming for 3-5 minutes in a 60°C heat bath.
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