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C5890 Sigma

Casein from bovine milk

suitable for substrate for protein kinase (after dephosphorylation), purified powder



Related Categories Biochemicals and Reagents, Casein and Other Milk Proteins, Proteins and Derivatives More...
form   purified powder
mp   280 °C (dec.)(lit.)
suitability   suitable for substrate for protein kinase (after dephosphorylation)



1 kg in poly bottle

5 kg in poly drum

500 g in poly bottle


Casein from bovine milk is a phosphoprotein. There are four main types of Casein which make up approximately 80% of the total protein in bovine milk: α-s1 Casein, α-s2 Casein, β-Casein, and κ-Casein. Casein is proposed to be the main protective constituent in milk.

Biochem/physiol Actions

Partial gastrointestinal digestion of casein is a rich source of bioactive peptides, such as β-casomorphin. However, bovine casein is not homogeneous; variants A1 and B do lead to production of β-casomorphin 7 production, while A2 does not.

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Safety Information

NONH for all modes of transport
WGK Germany 

Frequently Asked Questions

How does the storage temperature relate to shipping conditions?
The storage conditions that a Sigma-Aldrich catalog and label recommend for products are deliberately conservative. For many products, long-term storage at low temperatures will increase the time during which they are expected to remain in specification and therefore are labeled accordingly. Where short-term storage, shipping time frame, or exposure to conditions other than those recommended for long-term storage will not affect product quality, Sigma-Aldrich will ship at ambient temperature. The products sensitive to short-term exposure to conditions other than their recommended long-term storage are shipped on wet or dry ice. Ambient temperature shipping helps to control shipping costs for our customers. At any time, our customers can request wet- or dry-ice shipment, but the special handling is at customer expense if our product history indicates that the product is stable for regular shipment. http://www.sigmaaldrich.com/etc/medialib/docs/Sigma-Aldrich/General_Information/shippingandlong-termstoragev3.Par.0001.File.tmp/shippingandlong-termstoragev3.pdf
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My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
What is the composition of Product C5890, Casein from bovine milk?
The approximate casein composition of milk in grams per Liter is: alpha-s1 (12-15); alpha-s2 (3-4); beta (9-11); and kappa (2-4).
What is the molecular weight of the casein subunits in Product C5890, Casein from bovine milk?
The alpha-s1 = 22-23.7 kDa, alpha-s2 = 25 kDa, beta = 24 kDa and kappa = 19 kDa.
What is Product C5890, Casein from bovine milk, soluble in?
Casein is not water soluble. It can be suspended in 1 M sodium hydroxide at a concentration of 50 mg/mL, yielding a turbid, faint yellow solution.
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Protocols & Articles


HPLC Analysis of Tryptic Digest on BIOshell™ A160 Peptide C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tryptic Digest on BIOshell™ A160 Peptide C18
Keywords: Chromatography, High performance liquid chromatography

HPLC Analysis of α-Casein Tryptic Digest on BIOshell™ A160 Peptide C18

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of α-Casein Tryptic Digest on BIOshell™ A160 Peptide C18
Keywords: Chromatography, Detection methods, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Proteomics, Separation

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