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C7039 Sigma

Cefotaxime sodium salt

plant cell culture tested, BioReagent, powder

Synonym: Cefotaxim sodium salt

  • CAS Number 64485-93-4

  • Empirical Formula (Hill Notation) C16H16N5NaO7S2

  • Molecular Weight 477.45

  •  Beilstein Registry Number 5711411

  •  EC Number 264-915-9

  •  MDL number MFCD00079073

  •  PubChem Substance ID 24892923

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics A-F,
InChI Key   AZZMGZXNTDTSME-JUZDKLSSSA-M
product line   BioReagent
form   powder
application(s)   cell culture | plant: suitable
color   white to light yellow
solubility   H2O: soluble (aqueous solutions of pH 4.3-6.2 are stable up to 3 weeks at 2-8 °C.)
suitability   plant cell culture tested
Featured Industry   Agriculture
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   2-8°C

Description

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place. Keep in a dry place.

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

Cefotaxime, a cephalosporin antibiotic, is active against both gram-negative and gram-positive bacteria. In addition, cefotaxime blocks the division of cyanobacteria and lower plant organelles/plastids such as the photosynthetic organelles of Glaucophytes and chloroplasts of bryophytes.

General description

Chemical structure: ß-lactam

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
XI0250000

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Protocols & Articles

Protocols

Antibiotics - Plant Tissue Culture Protocol

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Keywords: Adsorption, Antibiotics, Antifungals, Condensations, Molecular biology

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Peer-Reviewed Papers
15

References

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