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C7118 Sigma-Aldrich

Cefdinir

≥95% (HPLC)

Synonym: syn-7-[2-(2-amino-4-thiazolyl)-2-hydroxyiminoacetamido]-3-vinyl-3-cephem-4-carboxylic acid, BMY-28488, FK-482, [6R-[6α-7beta(Z)]]-7-[[(2-Amino-4-thiazolyl)(hydroxyimino)acetyl]amino]-3-ethenyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

  • CAS Number 91832-40-5

  • Empirical Formula (Hill Notation) C14H13N5O5S2

  • Molecular Weight 395.41

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics by Mechanism of Action, Biochemicals and Reagents,
assay   ≥95% (HPLC)
form   solid
pKa    9.70
mp   170 °C
solubility   dilute HCl: slightly soluble
Mode of action   cell wall synthesis | interferes
antibiotic activity spectrum   Gram-negative bacteria
  Gram-positive bacteria
storage temp.   room temp

Description

Application

An advanced-generation, cephalosporin antibiotic. Used for its excellent and well balanced antibacterial activities against gram-positive and gram-negative bacteria.

Cefdinir was used to study bacterial infections caused by Staphylococcus aureus and Neisseria gonorrhoeae and the horizontal transfer of the ftsI gene in H. influenzae.

Biochem/physiol Actions

Cefdinir is an advanced generation amino-2-thiazolyl cephalosporin effective against Gram-positive and Gram-negative bacteria. It acts by disrupting the synthesis of the peptidoglycan layer of bacterial cell walls. It is also known to inhibit human neutrophil myeloperoxidases.

General description

Chemical structure: ß-lactam

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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