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  • C7401 - Anti-Lectin, Canavalia ensiformis antibody produced in rabbit

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C7401 Sigma-Aldrich

Anti-Lectin, Canavalia ensiformis antibody produced in rabbit

fractionated antiserum, lyophilized powder

Synonym: Anti-Con A, Anti-Jack Bean Concanavalin A

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Properties

Related Categories Alphabetical Index, Antibodies, Cell Biology, Cell Signaling and Neuroscience, Immune Cell Signaling and Blood,
conjugate   unconjugated
clone   polyclonal
biological source   rabbit
application(s)   indirect ELISA: 1:25,000
species reactivity   Canavalia ensiformis
form   lyophilized powder
storage temp.   2-8°C
packaging   vial of ~2 mL lyophilized antiserum
antibody form   fractionated antiserum
Quality Level   200
antibody product type   primary antibodies

Description

Immunogen

Jack Bean Concanavalin A (Con A).

Target description

Lectins are highly specific carbohydrate binding proteins useful in carbohydrate and cell membrane studies, as well as cell agglutination and typing techniques.

Physical form

Lyophilized from 0.01 M phosphate buffered saline, pH 7.2.

Reconstitution

Reconstitute with 2 mL deionized water.

Storage and Stability

Prior to reconstitution store the product at 2-8 °C. After reconstitution, the solution may be stored frozen in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage clarify the solution by centrifugation before use.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Biochem/physiol Actions

Concanavalin A is a lectin isolated from Canavalia ensiformis or Jack bean seeds. It has potent mitogenic effect on T cells and triggers the activity of both helper and suppressor T cells exhibiting immune regulator activity. Con A triggers autophagy by binding on the cell membrane glycoprotein and is internalized to the mitochondria. It activates immune response in liver and displays anti-hepatoma effect.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles

Articles

Antibody Basics

Immunoglobulins (Igs) are produced by B lymphocytes and secreted into plasma. The Ig molecule in monomeric form is a glycoprotein with a molecular weight of approximately 150 kDa that is shaped more ...
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Peer-Reviewed Papers
15

References

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