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C7522 Sigma-Aldrich

Calcium Ionophore A23187

≥98% (TLC), powder

Synonym: Antibiotic A 23187, Calimycin

  • CAS Number 52665-69-7

  • Empirical Formula (Hill Notation) C29H37N3O6

  • Molecular Weight 523.62

  •  Beilstein Registry Number 1096801

  •  EC Number 258-084-1

  •  MDL number MFCD00151202

  •  PubChem Substance ID 24277964

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Properties

Related Categories A - K, Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics by Mechanism of Action,
InChI Key   HIYAVKIYRIFSCZ-CYEMHPAKSA-N
Quality Level   PREMIUM
assay   ≥98% (TLC)
form   powder
color   white to light yellow
solubility   ethanol: 5 mg/mL (with heating. Solutions are stable for at least 3 months at -20 °C when protected from light and water contamination.)
  DMSO: 50 mg/mL (with heating or sonication. Solutions are stable for at least 3 months at -20 °C when protected from light and water contamination.)
Mode of action   cell membrane | interferes
antibiotic activity spectrum   Gram-positive bacteria
  fungi
storage temp.   2-8°C

Description

Application

Ionophore highly selective for Ca2+. Potentiates responses to NMDA but not quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

Packaging

1, 5, 10 mg in serum bottle

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DM4676000

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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