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C7629 Sigma-Aldrich

L-Citrulline

≥98% (TLC)

Synonym: (S)-2-Amino-5-ureidopentanoic acid, L-2-Amino-5-ureidovaleric acid

  • CAS Number 372-75-8

  • Empirical Formula (Hill Notation) C6H13N3O3

  • Molecular Weight 175.19

  •  Beilstein/REAXYS Number 1725416

  •  EC Number 206-759-6

  •  MDL number MFCD00064397

  •  PubChem Substance ID 24892975

  •  NACRES NA.32

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Properties

Related Categories Allium sativum (Garlic), Amino Acid, Amino acids, Application Index, Arginine Metabolism,
Quality Level   200
assay   ≥98% (TLC)
form   powder
application(s)   detection: suitable
color   white to off-white
SMILES string   N[C@@H](CCCNC(N)=O)C(O)=O
InChI   1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
InChI key   RHGKLRLOHDJJDR-BYPYZUCNSA-N

Description

Application

L-Citrulline has been used in ultra-performance liquid chromatography to validate, metabolites involved in the coordination of metamorphic processes.

Packaging

10 mg in autosample vial

5, 25 g in poly bottle

Biochem/physiol Actions

Intermediate in the production of nitric oxide from L-arginine by NO synthetase.

L-Citrulline, when orally administered is found to ameliorate the condition of sickle cell disease in humans. L-citrulline can be a replacement for L-arginine administration in case of defective NO synthetase. L-Citrulline supplementation is found to fulfill the purpose of NO-dependent signaling.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. C7629.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Characteristic Metabolites for Inborn Errors of Amino Acid Metabolism

Inborn errors of metabolism are caused by changes in specific enzymatic reactions and hundreds of different such alterations, which affect about 1 of every 5000 newborns, have been characterized. The...
Keywords: Indicators, Metabolism, Metabolites

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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